AgNOR
staining, colonic tubular adenoma, Image by G. Giuffré, University
Messina AgNOR
staining, colonic tubular adenoma, Image by G. Giuffré, University
Messina
AgNOR research has a tradition in the AMBA group. The first international "Workshop on AgNORs" was held from 1-3 October 1993 in our institute.
Homepage
of the Peter Hufnagl
Tel. +49-30-2802 5432
Fax: +49-30-2802 5668
e-mailPeter.Hufnagl@charite.de
Peters Homepage
Hans Guski
Tel. +49-30-2802 3479
Fax: +49-30-2802 5668
e-mail Hans.Guski@charite.de
Dietmar Stötzer
Tel. +49-30-2802 2883
Ali Khalili
Tel. +49-30-2802 3871
Edgard Ozourma
Tel. +49-30-2802 3871
Wolfram Kiene
Tel. +49-30-2802 3871
Babett Schick
Tel. +49-30-2802 3871
Rainer Boack
Tel. +49-30-2802 3871
Adam Czerwinski
Tel. +49-30-2802 3871
Lukas Günther
Tel. +49-30-2802 3871
Michael Beil
Tel. +49-201-723 5924
currently in Essen, Germany
Günter Wolf
Tel. +49-30-2802 3871
e-mail Guenter.Wolf@charite.de
Guenters Homepage
1991
Hufnagl, P.: Die Vermessung der Anzahl, Größe und Lage von AgNORs in histologischen Schnitten von Astrozytomen. Zentralbl. Pathol.137 (1991), 493-497
Martin, H., Beil, M., Hufnagl, P., Wolf, G. and G. Korek: Computer-assisted image analysis of nucleolar organizer regions (NORs). A pilot study of astrocytomas and glioblastomas. Acta Histochem. 90(1991), 189-196
Martin, H., Hufnagl, P., Wenzelides K. und M. Beil: AgNORs in Zellen von Urothelkarzinomen der Harnblase-eine quantitative Untersuchung mit Hilfe der automatisierten Mikroskopbildanalyse. Zentralbl. Pathol. 137 (1991), 505-509
1992
Martin, H., Gottschalk, J., Hufnagl, P. und M. Beil: AgNORs in der Neuroonkologie. Acta Histochem. , Suppl.-Band XLII 1992, 179-184
Martin, H., Hufnagl, P., Beil, M., Wenzelides, K., Gottschalk, J., Rahn, W.: Nucleolar Organizer region-associated proteins in cancer cells: Quantitative investigations on gliomas, meningiomas, urinary bladder carcinomas and pleural lesions. Anal. Quant. Cytol. Histol. 14 (1992), 312-319
1994
Hufnagl, P. and H. Guski: The role of AgNORs in tumor pathology. Zentralbl. Pathol. 140(1994), 1-2
Hufnagl, P., Guski, H. and H.-J. Schulz: Measuring of AgNORs using image analysis. Zentralbl. Pathol. 140(1994), 31-36
Biesterfeld, S., Ruoss, E., Hufnagl, P. and H. Martin: Influence of fixation and preparation on the AgNOR distribution in routinely processed breast cancer specimens. Zentralbl. Pathol. 140(1994), 41-48
Pedal, W.-P., Warzok, R.W., Hufnagl, P. and K. Roth: Nucleolar organizer regions (AgNORs) in astrocytic tumors. Zentralbl. Pathol. 140(1994), 89-94
Aubele, M., Biesterfeld, S., Derenzini, M., Hufnagl, P., Martin, M., Öfner, D., Ploton, D. and J. Rüschoff: Guidelines of AgNOR quantitation. Zentralbl. Pathol. 140(1994), 107
1995
Hufnagl, P., Tennstedt, C., Nguyen-Dobinsky, N., Vogel, M.: Bilddatenbanken zur Archivierung mikroskopischer und makroskopischer Bilder. Neue Möglichkeiten der Diagnoseunterstützung am Beispiel der Fetalpathologie.Ber. Path. 120 (1995), 23-25
Öfner, D., Aubele, M., Biesterfeld, S., Derenzini, M., Giminez-Mas, J., A., Hufnagl, P., Ploton, D., Trerè, D., Rüschoff, J.: Guidelines of AgNOR quantification - first update Virchows Arch 437 (1995), 341
1996
Martin, H., Greiner, K., Beil, M., Hufnagl, P.: Die Bedeutung von AgNOR für die Differenzierung laryngealer Dysplasien und des Larynxkarzinoms HNO 44 (1996), 22-26
Haberland, C., Martin, H., Guski, H., Hufnagl, P., Vogel, S.: AgNOR-Analyse bei Astrozytomen des Kindesalters Zentralbl. f. Neurochir. 57 (1996), 5-11
Abstracts and papers in conference proceedings
1994
Hufnagl, P., Schulz, H.-J. and H. Guski: AgNOR distribution pattern as a prognostic criterion. Anal. Quant. Cytol. Histol. 16(1994), 49
1995
Guski, H., Winzer, H.-J., Hufnagl, P., Krause, M.:Analysis of nucleolar organizer regions in atypical ductal hyperplasia and carcinoma in situ of the breast. Path. Res. Pract. 191 (1995), 222
Hufnagl, P., Guski, H., Schulz, H.-J.: Measurement, standardization and significance of features describing AgNOR patterns Path. Res. Pract. 191 (1995), 236
Hufnagl, P., Guski, H., Schulz, H.-J.: Messung, Standardisierung und Bedeutung von Merkmalen zur Beschreibung von AgNOR Mustern Verh. Dtsch. Ges. Path. 97 (1995), 592
Neudeck, H., Unger, M., Hufnagl, P., Graf, R., Vogel, M.: Diagnostic value of silver-stained nuclkeolar organizers regions in the cytotrophoblast of complete and partial hydatidiform moles Placenta 16 (1995), A53
Guski, H., Winzer K.-J., Hufnagl P. and M. Krause: Analyse Nucleolus organisierender Regionen bei atypischer duktaler Hyperplaise und Carcinoma in situ der Brustdrüse Verh. Dtsch. Ges. Path. 79 (1995), 474
1996
Hufnagl, P., Martin, H., Guski, H.: Diagnostic value of different features describing AgNOR patterns. Anal. Cell. Pathol. 10 (1996), 225
Guski, H., Hufnagl, P., Winzer, K.-J., Krause, M.: AgNOR analysis in carcinoma in situ of the breast. Anal. Cell. Pathol. 10 (1996), 223
Martin, H., Haberland, C., Hufnagl, P., Guski, H., Beil, M.: AgNOR quantification in astrocytic gliomas Anal. Cell. Pathol. 10 (1996), 223
Hufnagl, P., Guski, H Günther, L.: Measurement of AgNORs in immunohistochemically stained specimens using image analysis. Eur. J. Histochem. 40 (1996), 343
Neudeck, H., Unger, M., Hufnagl, P., Graf, R., Peters, K., Kalla, J., Vogel, M.: Wertigkeit argyrophiler Nukleolus Organisierender Regionen (AgNORs) Vergleich des zytotrophoblastären Proliferationsverhaltens bei Blasenmole und Partialmole. Verh. Dtsch. Ges. Path. 80 (1996), 437
1997
Guski,H., Winzer, K.-J., Hufnagl, P., Günther, L.: AgNOR analysis of ER-psitive and ER-negative breast cancer cells. Path. Res. Pract. 193 (1997), 115
Hufnagl, P., Martin, M., Guski, H.: Diagnostic value of different features describing AgNOR patterns. EJPathol Vol 3.1 (1997)
Guski, H., Winzer, K.-J., Hufnagl, P, Krause, M.: AgNORs and prognostic evaluation of atypical ductal hyperplasia and carcinoma in situ of the breast. EJPathol Vol 3.1 (1997)
Image analysis programs have been developed in several labs (Berlin, Bologna, Regensburg, Edinburgh). Commercial programs are available from